I think...mmm. Perhaps it's meant to say something like, "one mustn't sacrifice opportunity for safety". Or at least, one oughtn't do that without careful consideration of everything else.

[She pauses, chiming in with a sigh of her own.]

...Take Giorno, for instance. He frightens me a little, from how...familiar he is, in some ways. Some of his bearing, that is, and some of his...just something about him. So, perhaps I might feel like avoiding him for that. But if I do, I might miss out on far more than I realize, for the security of not feeling...pushed past those very narrow boundaries.